The role of local meaning in infants' fixations of natural scenes.

As infants view visual scenes every day, they must shift their eye gaze and visual attention from location to location, sampling information to process and learn. Like adults, infants' gaze when viewing natural scenes (i.e., photographs of everyday scenes) is influenced by the physical features of the scene image and a general bias to look more centrally in a scene. However, it is unknown how infants' gaze while viewing such scenes is influenced by the semantic content of the scenes. Here, we tested the relative influence of local meaning, controlling for physical salience and center bias, on the eye gaze of 4- to 12-month-old infants (N = 92) as they viewed natural scenes. Overall, infants were more likely to fixate scene regions rated as higher in meaning, indicating that, like adults, the semantic content, or local meaning, of scenes influences where they look. More importantly, the effect of meaning on infant attention increased with age, providing the first evidence for an age-related increase in the impact of local meaning on infants' eye movements while viewing natural scenes.

The cascading development of visual attention in infancy: Learning to look and looking to learn.

The development of visual attention in infancy is typically indexed by where and how long infants look, focusing on changes in alerting, orienting, or attentional control. However, visual attention and looking are both complex systems that are multiply determined. Moreover, infants' visual attention, looking, and learning are intimately connected. Infants learn to look, reflecting cascading effects of changes in attention, the visual system and motor control, as well as the information infants learn about the world around them. Furthermore infants' looking behavior provides the input infants use to perceive and learn about the world. Thus, infants look to learn about the world around them. A deeper understanding of development will be gained by appreciating the cascading effects of changes across these intertwined domains.

Examining infants' visual paired comparison performance in the US and rural Malawi.

Measures of attention and memory were evaluated in 6- to 9-month-old infants from two diverse contexts. One sample consisted of African infants residing in rural Malawi (N = 228, 118 girls, 110 boys). The other sample consisted of racially diverse infants residing in suburban California (N = 48, 24 girls, 24 boys). Infants were tested in an eye-tracking version of the visual paired comparison procedure and were shown racially familiar faces. The eye tracking data were parsed into individual looks, revealing that both groups of infants showed significant memory performance. However, how a look was operationally defined impacted some-but not other-measures of infant VPC performance. RESEARCH HIGHLIGHTS: In both the US and Malawi, 6- to 9-month-old infants showed evidence of memory for faces they had previously viewed during a familiarization period. Infant age was associated with peak look duration and memory performance in both contexts. Different operational definitions of a look yielded consistent findings for peak look duration and novelty preference scores-but not shift rate. Operationalization of look-defined measures is an important consideration for studies of infants in different cultural contexts.

A Novel Approach to Assessing Infant and Child Mental Rotation.

Mental rotation is a critically important, early developing spatial skill that is related to other spatial cognitive abilities. Understanding the early development of this skill, however, requires a developmentally appropriate assessment that can be used with infants, toddlers, and young children. We present here a new eye-tracking task that uses a staircase procedure to assess mental rotation in 12-, 24-, and 36-month-old children (N = 41). To ensure that all children understood the task, the session began with training and practice, in which the children learned to fixate which of two houses a giraffe, facing either left or right, would approach. The adaptive two-up, one-down staircase procedure assessed the children's ability to fixate the correct house when the giraffe was rotated in 30° (up) or 15° (down) increments. The procedure was successful, with most children showing evidence of mental rotation. In addition, the children were less likely to succeed as the angle of rotation increased, and the older children succeeded at higher angles of rotation than the younger children, replicating previous findings with other procedures. The present study contributes a new paradigm that can assess the development of mental rotation in young children and holds promise for yielding insights into individual differences in mental rotation.

Diversity and representation in infant research: Barriers and bridges toward a globalized science of infant development.

Psychological researchers have become increasingly concerned with generalized accounts of human behavior based on narrow participant representation. This concern is particularly germane to infant research as findings from infant studies are often invoked to theorize broadly about the origins of human behavior. In this article, we examined participant diversity and representation in research published on infant development in four journals over the past decade. Sociodemographic data were coded for all articles reporting infant data published in Child Development, Developmental Science, Developmental Psychology, and Infancy between 2011 and 2022. Analyses of 1682 empirical articles, sampling approximately 1 million participants, revealed consistent under-reporting of sociodemographic information. For studies that reported sociodemographic characteristics, there was an unwavering skew toward White infants from North America/Western Europe. To address a lack of diversity in infant studies and its scientific impact, a set of principles and practices are proposed to advance toward a more globally representative science.

An investigation of mental rotation in infancy using change detection.

Two experiments were conducted to examine mental rotation in 6- to 12-month-old infants (N = 166) using a change detection task. These experiments were replications of Lauer and Lourenco (Lauer et al., 2015; Lauer & Lourenco, 2016), using identical stimuli and variations of their procedure, including an exact replication conducted in a laboratory setting (Experiment 1), and an online assessment using Lookit (Scott et al.,2017; Scott & Schulz, 2017) (Experiment 2). Both experiments failed to replicate the results of the original study; in neither experiment did infants' behavior provide evidence that they mentally rotated the object. Results are discussed in terms of the robustness of mental rotation in infancy and about limits in our experimental procedures for uncovering perceptual and cognitive abilities in infants.

The development of visual attention in infancy: A cascade approach.

Visual attention develops rapidly and significantly during the first postnatal years. At birth, infants have poor visual acuity, poor head and neck control, and as a result have little autonomy over where and how long they look. Across the first year, the neural systems that support alerting, orienting, and endogenous attention develop, allowing infants to more effectively focus their attention on information in the environment important for processing. However, visual attention is a system that develops in the context of the whole child, and fully understanding this development requires understanding how attentional systems interact and how these systems interact with other systems across wide domains. By adopting a cascades framework we can better position the development of visual attention in the context of the whole developing child. Specifically, development builds, with previous achievements setting the stage for current development, and current development having cascading consequences on future development. In addition, development reflects changes in multiple domains, and those domains influence each other across development. Finally, development reflects and produces changes in the input that the visual system receives; understanding the changing input is key to fully understand the development of visual attention. The development of visual attention is described in this context.

Understanding developmental cascades and experience: Diversity matters.

This Presidential Address is aimed at considering how infant development can be understood in terms of developmental cascades. Adopting a developmental cascades approach may be especially useful for understanding development in infancy, when changes occur in multiple domains over relatively short time spans. Thinking about change in terms of developmental cascades highlights the role of the input in development, both in terms of how the input changes with development and in terms of how differences in the input lead to different developmental pathways. I reflect on how a developmental cascade perspective can help us understand the role of input and how development builds as the emergence and refinement of abilities changes the input and shapes the developmental pathways. Further, I emphasize that infants develop despite differences in the input, and that when studying infant development we should seriously consider the diversity of experience that infants encounter and how differences in experience (and input) shape the developmental cascade.

Expanded carrier screening for reproductive risk assessment: An evidence-based practice guideline from the National Society of Genetic Counselors.

Expanded carrier screening (ECS) intends to broadly screen healthy individuals to determine their reproductive chance for autosomal recessive (AR) and X-linked (XL) conditions with infantile or early-childhood onset, which may impact reproductive management (Committee Opinion 690, Obstetrics and Gynecology, 2017, 129, e35). Compared to ethnicity-based screening, which requires accurate knowledge of ancestry for optimal test selection and appropriate risk assessment, ECS panels consist of tens to hundreds of AR and XL conditions that may be individually rare in various ancestries but offer a comprehensive approach to inherited disease screening. As such, the term "equitable carrier screening" may be preferable. This practice guideline provides evidence-based recommendations for ECS using the GRADE Evidence to Decision framework (Guyatt et al., BMJ, 2008, 336, 995; Guyatt et al., BMJ, 2008, 336, 924). We used evidence from a recent systematic evidence review (Ramdaney et al., Genetics in Medicine, 2022, 20, 374) and compiled data from peer-reviewed literature, scientific meetings, and clinical experience. We defined and prioritized the outcomes of informed consent, change in reproductive plans, yield in identification of at-risk carrier pairs/pregnancies, perceived barriers to ECS, amount of provider time spent, healthcare costs, frequency of severely/profoundly affected offspring, incidental findings, uncertain findings, patient satisfaction, and provider attitudes. Despite the recognized barriers to implementation and change in management strategies, this analysis supported implementation of ECS for these outcomes. Based upon the current level of evidence, we recommend ECS be made available for all individuals considering reproduction and all pregnant reproductive pairs, as ECS presents an ethnicity-based carrier screening alternative which does not rely on race-based medicine. The final decision to pursue carrier screening should be directed by shared decision-making, which takes into account specific features of patients as well as their preferences and values. As a periconceptional reproductive risk assessment tool, ECS is superior compared to ethnicity-based carrier screening in that it both identifies more carriers of AR and XL conditions as well as eliminates a single race-based medical practice. ECS should be offered to all who are currently pregnant, considering pregnancy, or might otherwise biologically contribute to pregnancy. Barriers to the broad implementation of and access to ECS should be identified and addressed so that test performance for carrier screening will not depend on social constructs such as race.

The association between plasma choline, growth and neurodevelopment among Malawian children aged 6-15 months enroled in an egg intervention trial.

Choline is an essential micronutrient that may influence growth and development; however, few studies have examined postnatal choline status and children's growth and development in low- and middle-income countries. The aim of this observational analysis was to examine associations of plasma choline with growth and development among Malawian children aged 6-15 months enrolled in an egg intervention trial. Plasma choline and related metabolites (betaine, dimethylglycine and trimethylamine N-oxide) were measured at baseline and 6-month follow-up, along with anthropometric (length, weight, head circumference) and developmental assessments (the Malawi Developmental Assessment Tool [MDAT], the Infant Orienting with Attention task [IOWA], a visual paired comparison [VPC] task and an elicited imitation [EI] task). In cross-sectional covariate-adjusted models, each 1 SD higher plasma choline was associated with lower length-for-age z-score (-0.09 SD [95% confidence interval, CI -0.17 to -0.01]), slower IOWA response time (8.84 ms [1.66-16.03]) and faster processing speed on the VPC task (-203.5 ms [-366.2 to -40.7]). In predictive models, baseline plasma choline was negatively associated with MDAT fine motor z-score at 6-month follow-up (-0.13 SD [-0.22 to -0.04]). There were no other significant associations of plasma choline with child measures. Similarly, associations of choline metabolites with growth and development were null except higher trimethylamine N-oxide was associated with slower information processing on the VPC task and higher memory scores on the EI task. In this cohort of children with low dietary choline intake, we conclude that there were no strong or consistent associations between plasma choline and growth and development.

The impact of face masks on infants' learning of faces: An eye tracking study.

This preregistered study examined how face masks influenced face memory in a North American sample of 6- to 9-month-old infants (N = 58) born during the COVID-19 pandemic. Infants' memory was tested using a standard visual paired comparison (VPC) task. We crossed whether or not the faces were masked during familiarization and test, yielding four trial types (masked-familiarization/masked-test, unmasked-familiarization/masked-test, masked-familiarization/unmasked-test, and unmasked-familiarization/unmasked-test). Infants showed memory for the faces if the faces were unmasked at test, regardless of whether or not the face was masked during familiarization. However, infants did not show robust evidence of memory when test faces were masked, regardless of the familiarization condition. In addition, infants' bias for looking at the upper (eye) region was greater for masked than unmasked faces, although this difference was unrelated to memory performance. In summary, although the presence of face masks does appear to influence infants' processing of and memory for faces, they can form memories of masked faces and recognize those familiar faces even when unmasked.

A new perspective on the role of physical salience in visual search: Graded effect of salience on infants' attention.

We tested 6- and 8-month-old White and non-White infants (N = 53 total, 28 girls) from Northern California in a visual search task to determine whether a unique item in an otherwise homogeneous display (a singleton) attracts attention because it is a unique singleton and "pops out" in a categorical manner, or whether attention instead varies in a graded manner on the basis of quantitative differences in physical salience. Infants viewed arrays of four or six items; one item was a singleton and the other items were identical distractors (e.g., a single cookie and three identical toy cars). At both ages, infants looked to the singletons first more often, were faster to look at singletons, and looked longer at singletons. However, when a computational model was used to quantify the relative salience of the singleton in each display-which varied widely among the different singleton-distractor combinations-we found a strong, graded effect of physical salience on attention and no evidence that singleton status per se influenced attention. In addition, consistent with other research on attention in infancy, the effect of salience was stronger for 6-month-old infants than for 8-month-old infants. Taken together, these results show that attention-getting and attention-holding in infancy vary continuously with quantitative variations in physical salience rather than depending in a categorical manner on whether an item is unique. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Linking patterns of infant eye movements to a neural network model of the ventral stream using representational similarity analysis.

Little is known about the development of higher-level areas of visual cortex during infancy, and even less is known about how the development of visually guided behavior is related to the different levels of the cortical processing hierarchy. As a first step toward filling these gaps, we used representational similarity analysis (RSA) to assess links between gaze patterns and a neural network model that captures key properties of the ventral visual processing stream. We recorded the eye movements of 4- to 12-month-old infants (N = 54) as they viewed photographs of scenes. For each infant, we calculated the similarity of the gaze patterns for each pair of photographs. We also analyzed the images using a convolutional neural network model in which the successive layers correspond approximately to the sequence of areas along the ventral stream. For each layer of the network, we calculated the similarity of the activation patterns for each pair of photographs, which was then compared with the infant gaze data. We found that the network layers corresponding to lower-level areas of visual cortex accounted for gaze patterns better in younger infants than in older infants, whereas the network layers corresponding to higher-level areas of visual cortex accounted for gaze patterns better in older infants than in younger infants. Thus, between 4 and 12 months, gaze becomes increasingly controlled by more abstract, higher-level representations. These results also demonstrate the feasibility of using RSA to link infant gaze behavior to neural network models. A video abstract of this article can be viewed at https://youtu.be/K5mF2Rw98Is.

Natural Variability in Parent-Child Puzzle Play at Home.

Here, we observed 3- to 4-year-old children (N=31) and their parents playing with puzzles at home during a zoom session to provide insight into the variability of the kinds of puzzles children have in their home, and the variability in how children and their parents play with spatial toys. We observed a large amount of variability in both children and parents' behaviors, and in the puzzles they selected. Further, we found relations between parents' and children's behaviors. For example, parents provided more scaffolding behaviors for younger children and parents' persistence-focused language was related to more child attempts after failure. Altogether, the present work shows how using methods of observing children at a distance, we can gain insight into the environment in which they are developing. The results are discussed in terms of how variability in spatial toys and spatial play during naturalistic interactions can help us contextualize the conclusions we draw from lab-based studies.

"May I Grab Your Attention?": An Investigation Into Infants' Visual Preferences for Handled Objects Using Lookit as an Online Platform for Data Collection.

We examined the relation between 4- to 12-month-old infants' (N = 107) motor development and visual preference for handled or non-handled objects, using Lookit (lookit.mit.edu) as an online tool for data collection. Infants viewed eight pairs of objects, and their looking was recorded using their own webcam. Each pair contained one item with an easily graspable "handle-like" region and one without. Infants' duration of looking at each item was coded from the recordings, allowing us to evaluate their preference for the handled item. In addition, parents reported on their infants' motor behavior in the previous week. Overall, infants looked longer to handled items than non-handled items. Additionally, by examining the duration of infants' individual looks, we show that differences in infants' interest in the handled items varied both by infants' motor level and across the course of the 8-s trials. These findings confirm infant visual preferences can be successfully measured using Lookit and that motor development is related to infants' visual preferences for items with a graspable, handle-like region. The relative roles of age and motor development are discussed.

Developmental changes in natural scene viewing in infancy.

We extend decades of research on infants' visual processing by examining their eye gaze during viewing of natural scenes. We examined the eye movements of a racially diverse group of 4- to 12-month-old infants (N = 54; 27 boys; 24 infants were White and not Hispanic, 30 infants were African American, Asian American, mixed race and/or Hispanic) as they viewed images selected from the MIT Saliency Benchmark Project. In general, across this age range infants' fixation distributions became more consistent and more adult-like, suggesting that infants' fixations in natural scenes become increasingly more systematic. Evaluation of infants' fixation patterns with saliency maps generated by different models of physical salience revealed that although over this age range there was an increase in the correlations between infants' fixations and saliency, the amount of variance accounted for by salience actually decreased. At the youngest age, the amount of variance accounted for by salience was very similar to the consistency between infants' fixations, suggesting that the systematicity in these youngest infants' fixations was explained by their attention to physically salient regions. By 12 months, in contrast, the consistency between infants was greater than the variance accounted for by salience, suggesting that the systematicity in older infants' fixations reflected more than their attention to physically salient regions. Together these results show that infants' fixations when viewing natural scenes becomes more systematic and predictable, and that predictability is due to their attention to features other than physical salience. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Infant Eye Gaze While Viewing Dynamic Faces.

Research using eye tracking methods has revealed that when viewing faces, between 6 to 10 months of age, infants begin to shift visual attention from the eye region to the mouth region. Moreover, this shift varies with stimulus characteristics and infants' experience with faces and languages. The current study examined the eye movements of a racially diverse sample of 98 infants between 7.5 and 10.5 months of age as they viewed movies of White and Asian American women reciting a nursery rhyme (the auditory component of the movies was replaced with music to eliminate the influence of the speech on infants' looking behavior). Using an analytic approach inspired by the multiverse analysis approach, several measures from infants' eye gaze were examined to identify patterns that were robust across different analyses. Although in general infants preferred the lower regions of the faces, i.e., the region containing the mouth, this preference depended on the stimulus characteristics and was stronger for infants whose typical experience included faces of more races and for infants who were exposed to multiple languages. These results show how we can leverage the richness of eye tracking data with infants to add to our understanding of the factors that influence infants' visual exploration of faces.

Visual short-term memory for overtly attended objects during infancy.

We investigated limitations in young infants' visual short-term memory (VSTM). We used a one-shot change detection task to ask whether 4- and 8.5-month-old infants (N = 59) automatically encode fixated items in VSTM. Our task included trials that consisted of the following sequence: first a brief (500 ms) presentation with a sample array of two items, next a brief (300 ms) delay period with a blank screen, and finally a test array (2,000 ms) identical to the sample array except that the color of one of the two items is changed. In Experiment 1, we induced infants to fixate one item by rotating it during the sample (the other item remained stationary). In Experiment 2, none of the items rotated. In both experiments, 4-month-old infants looked equally at the fixated item when it did and did not change color, providing no evidence that they encoded in VSTM the fixated item. In contrast, 8.5-month-old infants in Experiment 1 preferred the fixated item when it changed color from sample to test. Thus, 4-month-old infants do not appear to automatically encode fixated items in VSTM.